Are you looking for a new role as a Culture Media Scientist? Do you want to work for a business that is growing at a rapid pace with lots of opportunity for the future? If so, this could be the role for you!
This role is a scientist position within the culture media team. The scientist's research will focus on the rational design and optimisation of culture media formulations for the proliferation and maturation of various cell types in bioreactor systems. The objective being to produce chemically defined culture media, which are animal component free and cost effective.
This role is offered on a full time permanent basis, with a business that also offers lots of other benefits that will make you feel truly at home whilst at work.
- Design and implement experiments on the rational design of culture media for selected cell types by a combination of media screening, optimisation and validation processes (This will utilise DoE)
- Develop and validate assays to characterise cell proliferation and differentiation
- Acquire datasets to characterise culture media & cell performance, using tools such as nutrient analysers and viable cell assays
- Analyse datasets from media screening to infer key media components / formulations or culture hypothesises
- Validate various cell cultures platform as models for bioreactor systems
- Apply a combination of manual and automated culturing techniques
- Utilise information from academic literature, suppliers, collaborators, and external advisers to steer the direction of culture media research
- Maintain an accurate record of experiments using an ELN
- Create SOP and risk assessment documentation
- Participate in group and project meetings and discussions
- Perform routine laboratory maintenance
- Maintain the confidentiality of the project and protocols
- General ad-hoc duties as required to support the departmental and organisation requirements
- Doctorate in either Life Sciences or related field e.g. biochemistry, cell biology or biotechnology or equivalent experience
- ≥1 year of industry experience or post-doctoral experience in academia
- Significant experience in aseptic technique and cell culture, preferably in the establishment, differentiation and maintenance of stem or primary cell types
- Expertise in the metabolism of mammalian cell cultures, and preferably development, screening, and optimisation of cell culture media formulations
- Expertise in characterising and quantifying cell proliferation and differentiation in monolayer, suspension or bioreactor cultures
- Experience of setting up and optimising cell-based processes to a robust, preferably industrial-level, standard
- Has demonstrated proficiency at driving R&D projects forward by rational experimental design and implementation
- Experienced and highly skilled at data analysis and inferring hypothesis using data processing and analysis software
- Excellent at record keeping of experimental work, including documenting reagent batches
- Expertise in characterisation of culture media in terms of nutrients, proteins, osmolarity and dissolved gases
- Experience of culturing cells in serum-free cell conditions, preferable in establishing protocols and adaption of cells
- Application of DoE (Design of Experiments) to rational experiment design
- Molecular biology expertise e.g. enzyme-based metabolism assays, protein quantification & PCR
- Hands-on experience of culturing cells in bioreactor systems
- Experience with high-throughput lab instrumentation e.g. liquid handling systems and high content imagers
- Experience of writing SOPs and risk assessments
Randstad CPE values diversity and promotes equality. No terminology in this advert is intended to discriminate against any of the protected characteristics that fall under the Equality Act 2010. We encourage and welcome applications from all sections of society and are more than happy to discuss reasonable adjustments and/or additional arrangements as required to support your application.
Candidates must be eligible to live and work in the UK.
For the purposes of the Conduct Regulations 2003, when advertising permanent vacancies we are acting as an Employment Agency, and when advertising temporary/contract vacancies we are acting as an Employment Business.