5 jobs found in oxford, south east

Are you looking for a new role as a Bioinformatician? Do you want to work for a business that is growing at a rapid pace with lots of opportunity for the future? If so, this could be the role for you!This role is for a Bioinformatician, you will play a key role to tackle challenging biological questions. You will work in close collaboration with bench scientists, contributing to the design of CRISPR experiments, analyse genomic and transcriptomics data and develop new bioinformatics pipelines to support our R&D programme and delivery of company-wide milestones. This role is offered on a full time permanent basis, with a business that also offers lots of other benefits that will make you feel truly at home whilst at work. Responsibilities: Develop and implement computational biology tools and software to support gene editing and research activities Analyse public databases to identify novel candidate genes to inform in-house experiments and review relevant literature to build strong scientific cases Generate and test hypotheses on genome-scale data using analytical and statistical methods Work in close collaboration with cell/molecular biologists; contribute to the collaboration by performing computational analyses to inform experimental design, answer biological questions, and guide decision-making for internal R&D programs Balance integration and extension of existing bioinformatics and next-generation sequencing (NGS) tools with the creation of new tools and algorithms as needed Engage in a highly collaborative environment with other scientists bringing a range of disciplines to the project to fully understand the value of computational approaches Prepare and deliver technical report to the R&D team and senior management Keep up to date with field developments General ad-hoc duties as required to support the departmental and organisation requirements Qualifications: PhD in Computational Biology or related field or MSc with equivalent follow-on experience≥ 1 years of industry experience or post-doctoral experience in cell line engineering and CRISPR editingEssential Experience:Extensive experience in analysing and interpreting genomic, NGS or other omics data sets Experience in programming and running complex analysis in R, MATLAB, Python or similar Experience working in human disease would be considered plus Knowledge of common ML approaches often applied to genomics data is desirable, but not essential Experience designing and performing cell & molecular biology assays Highly organised, self-motivated, and capable of working both independently and collaboratively, in a fast-paced team environment with shifting priorities A proven history of independent investigations and innovative thinking Randstad CPE values diversity and promotes equality. No terminology in this advert is intended to discriminate against any of the protected characteristics that fall under the Equality Act 2010. We encourage and welcome applications from all sections of society and are more than happy to discuss reasonable adjustments and/or additional arrangements as required to support your application.Candidates must be eligible to live and work in the UK.For the purposes of the Conduct Regulations 2003, when advertising permanent vacancies we are acting as an Employment Agency, and when advertising temporary/contract vacancies we are acting as an Employment Business.

Are you looking for a new role as a Molecular Biology Technician? Do you want to work for a business that is growing at a rapid pace with lots of opportunity for the future? If so, this could be the role for you!This role is for a Molecular Biology Technician within the Bioengineering team. As a Technician in the Bioengineering team you will be tasked with supporting the team activities for our client. This role is offered on a full time permanent basis, with a business that also offers lots of other benefits that will make you feel truly at home whilst at work. Responsibilities:Routine testing of cells on various materials Maintenance of mammalian cells lines including stem cells Performing various molecular based assays Shared responsibility for out-of-hours cell culture maintenance Expansion, culturing and banking of cells Preparation of cell culture reagents and media Tracking of consumables stock levels and reagents Adherence of standard operating procedures (SOPs) Recording all data produced in an electronic laboratory notebook systemDay-to-day housekeeping of dedicated laboratories General ad-hoc duties as required to support the departmental and organisation requirementsQualifications: A degree/ technical degree in Life sciences, Biology, Biomedical science, or equivalent experience in related fields.Essential Experience:Experienced in culturing mammalian cells and working under aseptic conditions Experience of testing materials with mammalian cells and appropriate assays Comfortable with routine day-to-day role Ability to prepare reagents, stock solutions and media for laboratory processes Ability to follow, execute and log detailed protocols Good numeracy and communication skills Computer literate and ability to familiarise with different IT systemsDesirable Experience:Familiar with a range of instruments associated with molecular biological analysis Experience of working in multidisciplinary laboratory Randstad CPE values diversity and promotes equality. No terminology in this advert is intended to discriminate against any of the protected characteristics that fall under the Equality Act 2010. We encourage and welcome applications from all sections of society and are more than happy to discuss reasonable adjustments and/or additional arrangements as required to support your application.Candidates must be eligible to live and work in the UK.For the purposes of the Conduct Regulations 2003, when advertising permanent vacancies we are acting as an Employment Agency, and when advertising temporary/contract vacancies we are acting as an Employment Business.

Are you looking for a new role as a Research Associate? Do you want to work for a business that is growing at a rapid pace with lots of opportunity for the future? If so, this could be the role for you!This role is a Research Associate within the culture media team. You will conduct scientific research to support the rational design and optimisation of culture media formulations. Specifically, media for the proliferation and maturation of various cell types in bioreactor systems. The objective being to produce chemically defined culture media, which are animal component free and cost effective. This role is offered on a full time permanent basis, with a business that also offers lots of other benefits that will make you feel truly at home whilst at work. Responsibilities:Maintenance of mammalian cell cultures (e.g. cell revival, culture and banking) both manually and automatedPreparation of reagents for cell culture and characterisation processes Characterise cellular samples for cell vitality (e.g. cell numbers, cell viability and cell sizing) and differentiation (e.g. select markers)Characterise spent media for secreted metabolites and nutrient consumptionProduce culture media stocks for screeningPerform quality tests on cells, reagents and media (e.g. contamination testing)Maintain an accurate record of experiments using an ELNAccurately report results (including contaminations and incidents)Create SOP and risk assessment documentationParticipate in group and project meetings and discussionsMaintain and organise laboratory consumable/reagent inventories (including purchasing)Perform routine laboratory maintenanceMaintain the confidentiality of the project and protocolsGeneral ad-hoc duties as required to support the departmental and organisation requirementsQualifications: Degree in either Life Sciences, Biochemistry, Biotechnology or related fieldEssential Experience:Good understanding of cell biology and biochemistryExperience of experimental design, execution, and data analysisExperience in aseptic technique and mammalian cell culture, preferably in the handling of stem or primary cell typesExperience of experimental record-keepingExperience of trouble shooting in an experimental capacityGood numeracy and communication skills (both written and verbal)Desirable Experience:Experienced with writing standard protocols, basic reports, and risk assessmentsKnowledge of and skills to use analysis instruments (e.g. cell counters, UV-vis plate readers & microscopes / imagers) Molecular biology skills e.g. enzyme-based metabolism assays, protein quantification & PCR Nutrient analysis and osmolarity characterisation experience Knowledge of culture media fundamentals Statistical analysis of dataExperience with automated lab instrumentation Randstad CPE values diversity and promotes equality. No terminology in this advert is intended to discriminate against any of the protected characteristics that fall under the Equality Act 2010. We encourage and welcome applications from all sections of society and are more than happy to discuss reasonable adjustments and/or additional arrangements as required to support your application.Candidates must be eligible to live and work in the UK.For the purposes of the Conduct Regulations 2003, when advertising permanent vacancies we are acting as an Employment Agency, and when advertising temporary/contract vacancies we are acting as an Employment Business.

Are you looking for a new role as a CRISPR Senior Scientist? Do you want to work for a business that is growing at a rapid pace with lots of opportunity for the future? If so, this could be the role for you!This role is for a Senior Scientist responsible for CRISPR development. You will be the go-to expert for gene editing, both single locus and genome-wide. Your experience in cell biology, molecular biology and cellular engineering will support our research programme and the delivery of company-wide milestones. Reporting to the Director of Cell Biology you will work with a team of scientists and the wider R&D department.This role is offered on a full time permanent basis, with a business that also offers lots of other benefits that will make you feel truly at home whilst at work. Responsibilities: Design, develop and implement gene editing technologies, processes and applications Responsible for the delivery of pooled CRISPR screening and base editing Ability to work closely with Bioinformatician in the design and analysis of CRISPR experiments Generation of Cas9 expressing cell lines, production of pooled lentivirus libraries and optimisation of screening conditions Execution of pooled CRISPR screens and preparation of samples for NGS Hit validation studies and stem cell differentiation Create Standard operation procedures and document experiments using electronic laboratory notebook system Engage with other teams and with external collaborators Prepare and deliver technical report to the R&D team and senior management Keep up to date with field developments and apply these to improve experimental design and assay performance General ad-hoc duties as required to support the departmental and organisation requirementsQualifications: A PhD in a relevant area of Biological Sciences or related field ≥ 5 years of post-doctoral or industry experience in cell line engineering and CRISPR editing Essential Experience:In-depth experience of complex CRISPR assay design & delivery including but not limited to CRISPRko, CRISPRa/i or base editing Experience in using key CRISPR bioinformatic tools and analysing CRISPR data (single gene level and multiplexed editing, eg from CRISPR screens) Proven experience and track record in executing techniques in molecular assays and molecular biology (qRT-PCR, scRNA seq, ddPCR, cloning, NGS) Experience in the maintenance and differentiation of stem cells Experience and knowledge of cellular assays and cell phenotyping (FACS, IHC, clonogenic, cytotoxicity and viability). Familiarity with the implementation, development and use of automation to support medium throughput gene editing Highly organised, self-motivated, and capable of working both independently and collaboratively; in a fast-paced team environment with shifting priorities A proven history of independent investigations and innovative thinking Randstad CPE values diversity and promotes equality. No terminology in this advert is intended to discriminate against any of the protected characteristics that fall under the Equality Act 2010. We encourage and welcome applications from all sections of society and are more than happy to discuss reasonable adjustments and/or additional arrangements as required to support your application.Candidates must be eligible to live and work in the UK.For the purposes of the Conduct Regulations 2003, when advertising permanent vacancies we are acting as an Employment Agency, and when advertising temporary/contract vacancies we are acting as an Employment Business.

Are you looking for a new role as a Research Technician? Do you want to work for a business that is growing at a rapid pace with lots of opportunity for the future? If so, this could be the role for you! As a Technician in the Cell biology Team you will be tasked with supporting the cell culture activities for our client. This role is offered on a full time permanent basis, with a business that also offers lots of other benefits that will make you feel truly at home whilst at work. Responsibilities: Maintenance of different mammalian cells lines including stem cells (MSCs, ESCs, iPSCs, satellite cells and adipocytes)Expansion, culturing and banking of cellsProvision of cell culture requirements to support multiple projects across the Research and Development teamShared responsibility for out-of-hours cell culture maintenancePreparation of cell culture reagents and mediaTracking of consumable stock levels and reagentsAdherence of standard operating procedures (SOPs)Recording all data produced in an electronic laboratory notebook systemDay-to-day housekeeping of dedicated laboratoriesGeneral ad-hoc duties as required to support the departmental and organisation requirements Qualifications:Degree in Life Sciences, Biotechnology or equivalent qualification in related field Essential Experience:Experienced in culturing mammalian cells and working under aseptic conditionsAbility to prepare reagents and media for laboratory processesGood problem-solving abilitiesGood numeracy and communication skillsComputer literate and ability to familiarise with different IT systems Desirable Experience:Experienced in maintenance and differentiation of mammalian stem cells including ESC and iPSCsExperience with cell isolation protocols from biological samples Randstad CPE values diversity and promotes equality. No terminology in this advert is intended to discriminate against any of the protected characteristics that fall under the Equality Act 2010. We encourage and welcome applications from all sections of society and are more than happy to discuss reasonable adjustments and/or additional arrangements as required to support your application.Candidates must be eligible to live and work in the UK.For the purposes of the Conduct Regulations 2003, when advertising permanent vacancies we are acting as an Employment Agency, and when advertising temporary/contract vacancies we are acting as an Employment Business.